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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIGD2B
All Species:
26.97
Human Site:
T43
Identified Species:
49.44
UniProt:
Q4VC39
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4VC39
NP_620175
106
11405
T43
K
E
K
F
L
R
K
T
R
E
N
P
V
V
P
Chimpanzee
Pan troglodytes
XP_523210
106
11357
T43
K
E
K
F
L
R
K
T
R
E
N
P
V
V
P
Rhesus Macaque
Macaca mulatta
XP_001084675
106
11638
T43
K
E
K
F
L
R
K
T
R
E
N
P
V
V
P
Dog
Lupus familis
XP_536423
106
11321
T43
K
E
K
F
L
R
K
T
R
E
N
P
M
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQJ1
106
11350
T43
K
E
K
F
I
R
K
T
R
E
N
P
M
V
P
Rat
Rattus norvegicus
Q8VH49
93
10283
P31
A
R
E
T
P
F
V
P
I
G
M
A
G
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514680
81
8548
Y19
W
P
A
S
V
F
P
Y
P
A
A
G
C
L
A
Chicken
Gallus gallus
XP_414550
124
13681
T61
A
D
K
F
R
R
K
T
R
E
N
P
L
V
P
Frog
Xenopus laevis
NP_001087828
93
10198
P31
I
R
K
V
K
E
N
P
F
V
P
I
G
C
L
Zebra Danio
Brachydanio rerio
NP_001017641
116
12208
T53
K
D
K
F
I
R
K
T
K
E
N
P
F
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573120
102
11395
I40
K
E
K
L
Q
R
K
I
K
E
N
P
L
V
P
Honey Bee
Apis mellifera
XP_001122466
103
11799
V41
K
E
R
M
I
R
K
V
K
E
N
P
I
I
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780376
117
12675
L49
R
E
K
L
I
K
K
L
K
Q
N
P
F
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
71.6
71.6
N.A.
74.5
35.8
N.A.
41.5
41.9
49
49.1
N.A.
40.5
35.8
N.A.
41.8
Protein Similarity:
100
99
82
82
N.A.
83.9
52.8
N.A.
53.7
59.6
63.2
68
N.A.
58.4
53.7
N.A.
55.5
P-Site Identity:
100
100
100
93.3
N.A.
86.6
0
N.A.
0
73.3
6.6
73.3
N.A.
66.6
53.3
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
13.3
86.6
6.6
93.3
N.A.
80
86.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
0
0
0
0
0
0
8
8
8
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
62
8
0
0
8
0
0
0
70
0
0
0
0
0
% E
% Phe:
0
0
0
54
0
16
0
0
8
0
0
0
16
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
8
16
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
31
0
0
8
8
0
0
8
8
8
0
% I
% Lys:
62
0
77
0
8
8
77
0
31
0
0
0
0
0
0
% K
% Leu:
0
0
0
16
31
0
0
8
0
0
0
0
16
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
8
0
16
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
77
0
0
0
0
% N
% Pro:
0
8
0
0
8
0
8
16
8
0
8
77
0
0
77
% P
% Gln:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
8
16
8
0
8
70
0
0
47
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
54
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
8
8
0
8
0
0
24
70
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _